The Piskounova Lab
Pershing Square 2021 Announcement Video
Dr. Piskounova was recently awarded the Pershing Square prize for the proposed work on tRNA modifications in metastasis, discussed below.
Situated on the Upper East Side of Manhattan:
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The Piskounova Lab is a member of the Sandra and Edward Meyer Cancer Center in the Belfer Research Building at Weill Cornell Medicine. Located on the Upper East Side of Manhattan, the Belfer Research Building is nestled amongst top scientific research institutions in NYC including Memorial Sloan Kettering and Rockefeller University.
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Memorial Sloan Kettering
Rockefeller University
Areas of Research
Metabolic Adaptation
What are the metabolic adaptations that enable survival and colonization of vital organs by metastasizing cancer cells?
Mechanisms of Stress resistance
Metastasis is a stressful multi-step process. What mechanisms of stress resistance are metastasizing cells most dependent on at different steps of the metastatic cascade?
Molecular plasticity
Metastasizing cells display increased degree of molecular plasticity. How is this achieved? What are the main regulatory hubs of plasticity that can be harnessed therapeutically?